Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain.
Subject: Cancer - PUBLISHED VIA Journal of Pain and Symptom Management
Author(s):
Johnson JR, Burnell-Nugent M, Lossignol D, Ganae-Motan ED, Potts R, Fallon MT
View Source >>
Related Studies:
Cannabidiolic acid-mediated selective down-regulation of c-fos in highly aggressive breast cancer MDA-MB-231 cells: possible involvement of its down-regulation in the abrogation of aggressiveness.
Published via Journal of Natural Medicines
Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.
Published via Biochemical Pharmacology
Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas.
Published via Journal of Neuro-Oncology
Cannabidiol inhibits angiogenesis by multiple mechanisms.
Published via British Journal of Pharmacology
Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture.
Published via Journal of Pharmacology and Experimental Therapeutics
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
Published via Author Manuscript
Cannabidiol as potential anticancer drug.
Published via British Journal of Clinical Pharmacology
Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents.
Published via Carcinogenesis
Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect.
Published via PLOS ONE
In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines
Published via Pharmacology & Pharmacy
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.
Published via Molecular Cancer Therapeutics
Cannabidiol Reduces Leukemic Cell Size – But Is It Important?
Published via Frontiers in Pharmacology
Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.
Published via Journal of Pharmacology and Experimental Therapeutics
Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression.
Published via Molecular Pharmacology
Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy.
Published via Molecular Cancer Therapeutics
Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.
Published via Author Manuscript
Anticancer activity of anandamide in human cutaneous melanoma cells.
Published via European Journal of Pharmacology
The influence of biomechanical properties and cannabinoids on tumor invasion.
Published via Cell Adhesion & Migration
Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.
Published via Author Manuscript
Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium.
Published via Genes & Cancer
Antitumorigenic targets of cannabinoids – current status and implications.
Published via Expert Opinion on Therapeutic Targets
Nabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial.
Published via Journal of Pain
Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.
Published via Journal of Molecular Medicine
TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer.
Published via Urology
A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells.
Published via International Immunopharmacology
Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target.
Published via Author Manuscript
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
Published via The FASEB Journal
Endocannabinoids in endocrine and related tumours.
Published via Endocrine-Related Cancer
Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells.
Published via Pharmaceutical Research
COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells.
Published via Molecular Cancer Therapeutics
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.
Published via Journal of Pharmacology and Experimental Therapeutics
Towards the use of non-psychoactive cannabinoids for prostate cancer.
Published via British Journal of Pharmacology
Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism.
Published via British Journal of Pharmacology
Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme.
Published via PLOS ONE
Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival.
Published via Author Manuscript
In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma.
Published via Current Oncology